EP1583772B1 EMPLOYMENT OF ROTAVIRUS PROTEINS, DERIVED PROTEINS AND PEPTIDES FOR THE MODULATION OF TISSUE PERMEABILITY
有权
基本信息:
- 专利标题： EMPLOYMENT OF ROTAVIRUS PROTEINS, DERIVED PROTEINS AND PEPTIDES FOR THE MODULATION OF TISSUE PERMEABILITY
- 专利标题（中）：轮状病毒蛋白应用导出调制组织渗透性由其和蛋白质肽
- 申请号：EP03700188.0 申请日：2003-01-10
- 公开(公告)号：EP1583772B1 公开(公告)日：2015-04-01
- 发明人： GONZALEZ-MARISCAL, Lorenza , NAVA-DOMINGUEZ, Porfirio
- 申请人： Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional
- 申请人地址： Av. Instituto Politécnico Nacional 2508 Col. San Pedro Zacatenco C.F,. C.P. 07360 MX
- 专利权人： Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional
- 当前专利权人： Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional
- 当前专利权人地址： Av. Instituto Politécnico Nacional 2508 Col. San Pedro Zacatenco C.F,. C.P. 07360 MX
- 代理机构： Webber, Philip Michael
- 国际公布： WO2003098991 20031204
- 主分类号： C07K14/14
- IPC分类号： C07K14/14
摘要：
The present invention refers to the use of rotavirus proteins VP4, VP8 and their derived fusion proteins and peptides, for enhancing the delivery of pharmaceutical agents through the paracellular pathway. These rotavirus proteins and derived peptides may additionally be employed to reduce unwanted cellular adhesion that can occur between cancerous cells, or between normal cells as a result of surgery, injury, chemotherapy, disease, inflammation or other pathological conditions.
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07K | 肽 |
| ------C07K14/00 | 具有多于20个氨基酸的肽；促胃液素；生长激素释放抑制因子；促黑激素；其衍生物 |
| --------C07K14/005 | .来自病毒 |
| ----------C07K14/01 | ..DNA病毒 |
| ------------C07K14/14 | ...呼吸道肠道病毒科，例如轮状病毒、兰舌病毒、科洛拉多蜱热病毒 |