基本信息:
- 专利标题： PYRAZOLOPYRIMIDINES AS CYCLIN-DEPENDENT KINASE INHIBITORS
- 专利标题（中）：用于治疗癌症SUITABLE吡
- 申请号：EP03794592.0 申请日：2003-09-03
- 公开(公告)号：EP1537116A1 公开(公告)日：2005-06-08
- 发明人： GUZI, Timothy, J. , PARUCH, Kamil , DWYER, Michael, P. , DOLL, Ronald, J. , GIRIJAVALLABHAN, Viyyoor, Moopil , MALLAMS, Alan , ALVAREZ, Carmen, S. , KEERTIKAR, Kartik, M. , RIVERA, Jocelyn , CHAN, Tin-Yau , MADISON, Vincent , FISCHMANN, Thierry, O. , DILLARD, Lawrence, W. , TRAN, Vinh, D. , HE, Zhen Min , JAMES, Ray, Anthony , PARK, Haengsoon , PARADKAR, Vidyadhar, M. , HOBBS, Douglas, Walsh
- 申请人： SCHERING CORPORATION , Pharmacopeia Drug Discovery, Inc.
- 申请人地址： 2000 Galloping Hill Road Kenilworth,New Jersey 07033-0530 US
- 专利权人： SCHERING CORPORATION,Pharmacopeia Drug Discovery, Inc.
- 当前专利权人： PHARMACOPEIA, LLC, US
- 当前专利权人地址： PHARMACOPEIA, LLC, US
- 代理机构： UEXKÜLL & STOLBERG
- 优先权： US408027P 20020904; US421959P 20021029
- 国际公布： WO2004022561 20040318
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519
摘要：
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D487/00 | 在稠环系中含有氮原子作为仅有的杂环原子的杂环化合物，不包含在C07D451/00至C07D477/00组中 |
| --------C07D487/02 | .在稠合系中含有两个杂环 |
| ----------C07D487/04 | ..邻位稠合系 |