基本信息:
- 专利标题： Processes for producing optically active 2-amino-1-phenylethanol derivatives
- 专利标题（中）：一种制备光学活性的2-氨基-1-苯基乙醇衍生物的方法
- 申请号：EP99102724.4 申请日：1994-11-18
- 公开(公告)号：EP0924194A2 公开(公告)日：1999-06-23
- 发明人： Furukawa, Kazuaki
- 申请人： DAICEL CHEMICAL INDUSTRIES, LTD.
- 申请人地址： 1, Teppo-cho Sakai-shi, Osaka 590 JP
- 专利权人： DAICEL CHEMICAL INDUSTRIES, LTD.
- 当前专利权人： DAICEL CHEMICAL INDUSTRIES, LTD.
- 当前专利权人地址： 1, Teppo-cho Sakai-shi, Osaka 590 JP
- 代理机构： HOFFMANN - EITLE
- 优先权： JP28941993 19931118; JP31904693 19931124; JP4017294 19940310; JP8301494 19940421; JP18321794 19940804
- 主分类号： C07C213/04
- IPC分类号： C07C213/04 ; C07C213/08 ; C07C213/10
摘要：
A process is provided for producing a 2-amino-1phenylethanol derivative comprising;
allowing (a) a compound shown by the general Formula (III)
or (b) a compound shown by the general Formula (IV)
wherein R 1 , R 2 , R 3 , R 4 and R 5 represent a hydrogen atom etc; Z represents a hydrogen atom or a protective group for hydroxyl group and X represents a halogen atom,
to react with a compound of the Formula Y-NH 2 wherein Y represents a hydrogen atom or a group which can be left in the reaction, further, when Y is the group which can be left in the reaction, allowing Y to be left,
to obtain a compound shown by the general Formula (VI)
which comprises adding an acid to the reaction products containing the compound of the general Formula (VI) to precipitate or crystallize said compound as a salt and, thereby, isolating the compound of the general Formula (VI).
allowing (a) a compound shown by the general Formula (III)
or (b) a compound shown by the general Formula (IV)
wherein R 1 , R 2 , R 3 , R 4 and R 5 represent a hydrogen atom etc; Z represents a hydrogen atom or a protective group for hydroxyl group and X represents a halogen atom,
to react with a compound of the Formula Y-NH 2 wherein Y represents a hydrogen atom or a group which can be left in the reaction, further, when Y is the group which can be left in the reaction, allowing Y to be left,
to obtain a compound shown by the general Formula (VI)
which comprises adding an acid to the reaction products containing the compound of the general Formula (VI) to precipitate or crystallize said compound as a salt and, thereby, isolating the compound of the general Formula (VI).
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07C | 无环或碳环化合物 |
| ------C07C213/00 | 制备含与同一个碳架连接的氨基和羟基，氨基和醚化的羟基或氨基和酯化的羟基的化合物 |
| --------C07C213/04 | .氨或胺与烯烃氧化物或卤代醇的反应 |