发明公开
EP0470756A2 Ruthenium-phosphine complex useful as catalyst and intermediate for synthesis thereof
失效
基本信息:
- 专利标题： Ruthenium-phosphine complex useful as catalyst and intermediate for synthesis thereof
- 专利标题（中）：Rathenium膦络合物可用作催化剂及其制造中间体。
- 申请号：EP91307028.0 申请日：1991-07-31
- 公开(公告)号：EP0470756A2 公开(公告)日：1992-02-12
- 发明人： Noyori, Ryoji , Kitamura, Masato , Sayo, Noboru , Kumobayashi, Hidenori , Giles, Martin F.
- 申请人： Takasago International Corporation
- 申请人地址： 19-22, Takanawa 3-chome Minato-ku Tokyo JP
- 专利权人： Takasago International Corporation
- 当前专利权人： Takasago International Corporation
- 当前专利权人地址： 19-22, Takanawa 3-chome Minato-ku Tokyo JP
- 代理机构： Dixon, Donald Cossar
- 优先权： JP204166/90 19900801
- 主分类号： C07F15/00
- IPC分类号： C07F15/00 ; B01J31/24
摘要：
A ruthenium-phosphine complex is represented by formula (I) :
wherein R 2- BINAP represents a tertiary phosphine compound represented by formula (II) :
where R 2 is a hydrogen atom or a methyl, methoxy or a t-butyl, X is a halogen atom ; and R and R 1 each represent is an optionally substituted phenyl group, e. g. substituted with alkyl, alkoxy or dialkylamino. A novel rutheniumphosphine complex used as starting material is represented by formula (III) :
wherein R and R 1 are as above and dma represents N,N-dimethylacetamide and is reacted with BINAP in a solvent to make the complex (I).
The complex of formula (I) is useful as a catalyst for general organic syntheses with its ligand being an optically inactive compound or for asymmetric syntheses with its ligand being an optically active compound, and can be prepared at a low cost.
摘要（中）：
wherein R 2- BINAP represents a tertiary phosphine compound represented by formula (II) :
where R 2 is a hydrogen atom or a methyl, methoxy or a t-butyl, X is a halogen atom ; and R and R 1 each represent is an optionally substituted phenyl group, e. g. substituted with alkyl, alkoxy or dialkylamino. A novel rutheniumphosphine complex used as starting material is represented by formula (III) :
wherein R and R 1 are as above and dma represents N,N-dimethylacetamide and is reacted with BINAP in a solvent to make the complex (I).
The complex of formula (I) is useful as a catalyst for general organic syntheses with its ligand being an optically inactive compound or for asymmetric syntheses with its ligand being an optically active compound, and can be prepared at a low cost.
钌 - 膦配合物是式（I）表示：其中，R <2> -BINAP darstellt由式表示的叔膦化合物（II）：其中R <2>是一个氢原子或甲基 基，甲氧基或叔丁基，X是卤原子; R和R <1>分别表示为任选substituiertem苯基，E。 克 烷基，烷氧基或二烷基氨基substituiertem。 用作起始材料的新型rutheniumphosphine络合物由式（III）表示： worin R和R <1>是N，N-二甲基乙酰胺如上述和DMA darstellt并进行反应与BINAP在溶剂中，使复合物（ 我）。 式（I）的配合物是作为与它的配体是具有光学活性的化合物或与其配体是光学活性的化合物不对称合成一般的有机合成中用作催化剂的，并能以低成本制备。
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07F | 含除碳、氢、卤素、氧、氮、硫、硒或碲以外的其他元素的无环，碳环或杂环化合物 |
| ------C07F15/00 | 含周期表第Ⅷ族元素的化合物 |