The utility model relates to a bone tissue biopsy needle. The bone drilling device comprises an outer sleeve for drilling a bone, an opening needle and a sampling tube, the sampling pipe is a hollow pipe body; one end of the sampling pipe is a sampling end; a holding block is fixed at the other end; a hole communicated with the interior of the sampling tube is formed in the holding block; the outer diameter of the sampling pipe is matched with the inner diameter of the outer sleeve, a clamping piece is slidably connected into the sampling pipe, a driving rod for driving the clamping piece to extend out of the sampling end of the sampling pipe to clamp a sample is arranged in the sampling pipe, one end of the driving rod is located in the sampling pipe, and the other end of the driving rodis exposed out of a hole in the holding block. The sample taking device has the advantages that when samples are taken, the operation is convenient, the fixation is firm, the shapes of the taken samples are regular, and more samples can be taken out.