The utility model relates to a regional personnel access management system of handling official business, including host system, vehicle perception detection device, license plate scanning device, identity verification module, the ware of punching the card, registry system, identifying code transmitting element, two -dimensional code scanning element, access control system, database and display module, equal and the host system interconnect of vehicle perception detection device, identity verification module and registry system, the output of vehicle perception detection device, punch the cardware and two -dimensional code scanning element links to each other with host system's input, the identifying code transmitting element respectively with registry system, mobile terminal interconnect, the output of database links to each other with host system's input. The utility model discloses it is intelligent higher, monitor the convenience, reduce guardianship personnel's working strength,register carrying out personnel through vehicle scanning device, mobilephone terminal scanning two -dimensional code and the device of punching the card, can follow the trail of business turn over personnel record by convenience of customers, improve the security performance.