The utility model belongs to the technical field of analytic chemistry, and discloses an ion chromatography device suitable for being sealed in a glove box for use. The ion chromatography device comprises a leacheate conveying system, a sample feeding system, a separating system, an inhibitor, a detector, a signal amplifier, a data processing system and a circuit controlling system, wherein the sample feeding system, the separating system, the inhibitor, the detector and the signal amplifier are placed in the glove box; the leacheate conveying system, the circuit controlling system and the data processing system are positioned outside the glove box; the leacheate conveying system is connected with the sample feeding system by virtue of a feed liquid conveying pipeline, and a conductivity signal output by the detector is connected with the data processing system by virtue of a data line after being amplified by the signal amplifier. The ion chromatography device has the advantages of being simple to operate, small in volume, capable of being placed in the glove box and capable of realizing accurate analysis of the content of ions in a radioactive sample.