The utility model discloses a three-dimensional logistics system based on radio frequency identification. The three-dimensional logistics system comprises a three-dimensional storehouse and a three-dimensional storehouse control circuit, the three-dimensional storehouse comprises a multi-layer storage rack and a three-dimensional motion body, RFID tags are pasted on the top faces of cargo tanks, the three-dimensional motion body comprises a rotary lead screw, a motion lead screw and a vertical column, the top of the multi-layer storage rack is fixedly connected with a first motor, one end of the motion lead screw is fixedly connected with a second motor, the vertical column is fixedly connected with a third motor, a winding drum is fixedly connected to an output shaft of the third motor, a steel wire rope is wound on the winding drum, and a fork is connected to the bottom of the steel wire rope. The three-dimensional storehouse control circuit comprises a microcontroller module, a power module, a radio frequency identification circuit, an RS-232 communication circuit, a liquid crystal display circuit, a voice play circuit, a first motor drive circuit module, a second motor drive circuit module and a third motor drive circuit module. The three-dimensional logistics system is simple in structure, convenient and fast to use and operate, high in cargo storing and taking efficiency and high in safety.