The utility model discloses a real-time transformer substation monitoring system. The system comprises a control computer, a video monitoring device, a ZigBee wireless gateway and an alarm host. The video monitoring device and the alarm host are connected with the control computer. The ZigBee wireless gateway is connected with the alarm host. The ZigBee wireless gateway is connected with a temperature and humidity sensor, a sulfur hexafluoride monitoring sensor, a water leakage detection sensor, an air-conditioning controller, a dehumidifier controller and a draught fan controller through a ZigBee wireless communication network. The temperature and humidity sensor, the sulfur hexafluoride monitoring sensor, the water leakage detection sensor, the air-conditioning controller, the dehumidifier controller and the draught fan controller transmit detected data to the alarm host through the ZigBee wireless communication network and the ZigBee wireless gateway. The real-time transformer substation monitoring system of the utility model possesses the following advantages that high intelligent real-time monitoring is performed on a transformer substation; working quality and efficiency of the transformer substation are increased and so on.