The utility model provides a quartz crystal microbalance sensor based on titanium base three-layer metal films. The sensor comprises a quartz crystal sheet (1), wherein a titanium plating film layer (2) is arranged on the surface of the quartz crystal sheet (1), a silver plating film layer (3) is arranged on the surface of the titanium plating film layer (2), a gold plating film layer (4) is arranged on the surface of the silver plating film layer (3), and the quartz crystal microbalance sensor based on the titanium base three-layer metal films is formed. The sensor provided by the utility model has the effects and beneficial points that the quartz crystal microbalance sensor based on the titanium base three-layer metal films has the advantages that the manufacture is simple, the cost is low, the sensitivity is high, the anticorrosion performance and the stability are good, and the like; and the quartz crystal microbalance sensor based on the titanium base three-layer metal films is superior to the traditional quartz crystal microbalance sensor.