The utility model relates to a drug releasing structure having local holes with drugs for drug elution apparatus comprising an apparatus body, holes which are directly prepared by the materials of the apparatus body, and active drugs which are stored in the holes, wherein the apparatus body adopts medical materials with great biocompatibility, and concluding or not concluding an outermost film, at least one of the local surfaces of the apparatus body raw materials is provided with single-size, or double-size or multi-size holes on the portion which is contacted with the pathological tissue, wherein the holes are a kind of countless homogeneous size distribution holes or two or more kinds of countless inhomogeneous size distribution holes comprising statistic mean of core diameter or core depth. The aiming local drug elution scheme adopted by the utility model effectively decreases the danger of causing thrombosis caused by slower endothelium transform after implanting the prior drug elution apparatus into human tissue, and the optimal combination and distribution of the multi-size holes more effectively controls the carrying capacity and releasing speed of the drugs, thereby achieving ideal therapy effect.