
基本信息:
- 专利标题: 用于促进和增强神经修复和再生的肌肉来源的细胞(MDC)
- 专利标题(英):Muscle derived cells(mdc) for promoting and enhancing nerve repair and regeneration
- 申请号:CN200480018035.2 申请日:2004-04-26
- 公开(公告)号:CN1812800A 公开(公告)日:2006-08-02
- 发明人: M·B·钱切洛尔 , J·瓦尔 , B·明纳里
- 申请人: 匹兹堡大学
- 申请人地址: 美国宾夕法尼亚州
- 专利权人: 匹兹堡大学
- 当前专利权人: 匹兹堡大学联邦制高等教育
- 当前专利权人地址: 美国宾夕法尼亚州
- 代理机构: 中国专利代理(香港)有限公司
- 代理人: 李波; 王景朝
- 优先权: 60/465,846 2003.04.25 US
- 国际申请: PCT/US2004/013115 2004.04.26
- 国际公布: WO2004/096245 EN 2004.11.11
- 进入国家日期: 2005-12-26
- 主分类号: A61K35/34
- IPC分类号: A61K35/34 ; A61P25/00
The present invention describes methods involving the use of muscle derived cells (MDCs), preferably obtained from skeletal muscle, to support the innervation and repair of damaged tissues and organs, particularly associated with nerve damage or neuropathy. The invention relates to MDCs for use in methods for promoting or enhancing innervation of nerve cells, particularly in the peripheral nervous system, and their ability to contribute to the development of neuronal tissue when MDCs are introduced at or near a tissue or organ site in need of repair due to injury, damage, disease, or dysfunction. Such methods are useful for the treatment of central and peripheral nervous system disorders and to alleviate, abate, or eliminate the symptoms of neurologic or neurodegenerative diseases in animals, particularly mammals, including humans. The methods are also useful for treating both nerve and muscle tissue following injury, damage, or dysfunction to these tissue types.
公开/授权文献:
- CN1812800B 用于促进和增强神经修复和再生的肌肉来源的细胞(MDC) 公开/授权日:2013-01-16
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K35/00 | 含有其有不明结构的原材料或其反应产物的医用配制品 |
--------A61K35/02 | .来源于非生命物质的 |
----------A61K35/34 | ..肌肉;心脏 |