基本信息:
- 专利标题： 形成非切除性心脏传导阻滞的系统和方法
- 专利标题（英）：System and method for forming a non-ablative cardiac conduction block
- 申请号：CN03810133.5 申请日：2003-05-07
- 公开(公告)号：CN1649641A 公开(公告)日：2005-08-03
- 发明人： 兰德尔·李
- 申请人： 加利福尼亚大学董事会
- 申请人地址： 美国加利福尼亚州
- 专利权人： 加利福尼亚大学董事会
- 当前专利权人： 加利福尼亚大学董事会
- 当前专利权人地址： 美国加利福尼亚州
- 代理机构： 北京集佳知识产权代理有限公司
- 代理人： 王学强
- 优先权： 60/379,140 2002.05.08 US; 60/426,058 2002.11.13 US; 60/429,914 2002.11.29 US; 60/431,287 2002.12.06 US; 10/329,295 2002.12.23 US; 10/349,323 2003.01.21 US
- 国际申请： PCT/US2003/014879 2003.05.07
- 国际公布： WO2003/095016 EN 2003.11.20
- 进入国家日期： 2004-11-04
- 主分类号： A61M31/00
- IPC分类号： A61M31/00
A system forms a cardiac conduction block at a location in a heart of a patient, generally without substantially ablating cardiac tissue. The system includes a delivery system coupled to a source of material that is substantially non-ablative with respect to cardiac tissue but that substantially interrupts and thus blocks cardiac conduction. The delivery system delivers the material to the location, and the material at the location forms a conduction block without substantially ablating the cardiac cells there. The material includes a synthetic polymer, a polysaccharide (e.g. block polysaccharide, alginate, etc.), or a protein, or an analog, derivative, precursor, or agent thereof, or a combination or blend thereof. The material may include living cells. The delivery assembly may include a needle for injecting the material. An expandable member is provided with a needle assembly to deliver the material and form a non-ablative circumferential conduction block where a pulmonary vein extends from an atrium.