基本信息:
- 专利标题： 单一聚合度的甘露糖醛酸的制备方法及应用
- 专利标题（英）：Preparation method of mannuronic acid with single degree of polymerization and its application
- 申请号：CN00111368.2 申请日：2000-09-07
- 公开(公告)号：CN1341665A 公开(公告)日：2002-03-27
- 发明人： 管华诗 , 刘岩 , 江晓路
- 申请人： 青岛海洋大学
- 申请人地址： 山东省青岛市鱼山路5号
- 专利权人： 青岛海洋大学
- 当前专利权人： 青岛海洋大学
- 当前专利权人地址： 山东省青岛市鱼山路5号
- 代理机构： 青岛海昊专利事务所
- 代理人： 崔清晨
- 主分类号： C08B37/00
- IPC分类号： C08B37/00
The preparation method of mannuronic acid with single polymerization degree includes the folloiwng steps: dissolving sodium alginate in water, adding algin lyase to make reaction, heating with boiling water bath to deactivate lyase, centrifugalizing and removing precipitate impurity, regulating pH value of the obtained solution, centrifugalizing and removing produced precipitate, using alkali liquor to dissolve and regulating pH value, adding ethyl alcohol to produce precipitate, drying and using ion exchange chromatographic column to make separation, using eluent to make elution. It is characterized by that the pH regulation range of the above-mentioned solution is 2.5-3.2, eluent is a gradient one of sodium acetate, and the described enzyme is a specific algin lyase produced by vibrio. Said invented product possesses antitumor activity, can be used for developing antitumor medicine.
公开/授权文献:
- CN1117766C 单一聚合度的甘露糖醛酸的制备方法 公开/授权日：2003-08-13
IPC结构图谱:
| C | 化学；冶金 |
| --C08 | 有机高分子化合物；其制备或化学加工；以其为基料的组合物 |
| ----C08B | 多糖类；其衍生物 |
| ------C08B37/00 | 不包括在C08B1/00至C08B35/00组内的多糖类的制备；其衍生物 |