The health-care medicinal wine is made up of the following Chinese herbal medicines of notoginseng root, salvia root, zedoary, multi-flower knotweed root, ginkgo leaf, ligustrum fruit, polygonatum root, centipede and nardostachys root as raw materials according to the conventional preparation method of medicinal wine. The above-mentioned Chinese medicinal materials are crushed and made into coarse flour, thend istillate wine and rice wine are added according to the raw material weight ratio of 1:(9-10), the weight ratio of distillate wine and rice wine is (3.5-4.5):1, then those are uniformlymixed, sealed, stirred once a day, after 30-35 days, settled and filtered, so that the invented product can be obtained. Said invention can improve blood microcirculation of human body, and has the functions of preventing and curing angio cardiopathy and cerebrovascular disease and sedation and tranquilization.