
基本信息:
- 专利标题: 一种肿瘤疫苗及其制备方法
- 专利标题(英):Tumor vaccine and preparation method thereof
- 申请号:CN201810772210.0 申请日:2018-07-13
- 公开(公告)号:CN110711205A 公开(公告)日:2020-01-21
- 发明人: 李政媛 , 王超
- 申请人: 北京中台恒基生物技术有限公司
- 申请人地址: 北京市海淀区苏州街33号7层706
- 专利权人: 北京中台恒基生物技术有限公司
- 当前专利权人: 北京中台恒基生物技术有限公司
- 当前专利权人地址: 北京市海淀区苏州街33号7层706
- 代理机构: 北京同立钧成知识产权代理有限公司
- 代理人: 彭雪瑞; 黄健
- 主分类号: A61K35/17
- IPC分类号: A61K35/17 ; A61K39/00 ; A61P35/00 ; C12N5/0784
The invention provides a tumor vaccine and a preparation method thereof. The tumor vaccine contains dendritic cells blocking CD11b molecular signaling pathways. The invention further provides the method for preparing the tumor vaccine. The method comprises the steps that (1) mononuclear cells are obtained from peripheral blood of mammals and induced into mature dendritic cells, or bone marrow hematopoietic precursor cells are obtained from bone marrows of the mammals and induced into mature dendritic cells; (2) the CD11b molecular signaling pathways of the mature dendritic cells are blocked; and (3) the dendritic cells blocking the CD11b molecular signaling pathways are collected. The provided tumor vaccine has the good anti-tumor effect, meanwhile, is wide in anti-tumor spectrum, and hasgood using safety.
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K35/00 | 含有其有不明结构的原材料或其反应产物的医用配制品 |
--------A61K35/02 | .来源于非生命物质的 |
----------A61K35/14 | ..血液 |
------------A61K35/17 | ...淋巴细胞;B细胞;T细胞;自然杀伤细胞;干扰素激活或细胞因子激活的淋巴细胞 |