Theinvention provides a platform loading and unloading port docking device suitable for railway cold-chain logistics. The platform loading and unloading port docking device of railway cold-chain logistics comprises a heat preservation channel, a docking mechanism, a lifting door and a hydraulic telescopic mechanism, wherein the a track for operation is arranged under the heat preservation channel,and the heat preservation channel can slide along the track; the docking mechanism is installed at the end, close to the railway, of the heat preservation channel, and comprises an inflatable door seal which can be expanded outwards by inflating and fitted with a railway mechanical refrigeration car, and the gap between the heat preservation channel and the railway mechanical refrigeration car isfilled; a first isolation door (lifting door) and a second isolation door (lifting door) are arranged at the two ends of the heat preservation channel; the hydraulic telescopic mechanism can telescope and move up and down, and is connected to the car door of the railway mechanical refrigeration car in an overlapped mode. According to the platform loading and unloading port docking device of railway cold-chain logistics, the technical problems existing in the prior art that refrigerated goods are directly in contact with air in the process of transportation between the railway mechanical refrigeration car and a railway cold storage, thus the quality of the goods is lowered can be alleviated.