The invention discloses a composite production device for an extracellular matrix dressing. The composite production device comprises a box, a channel and a feeding area, wherein the channel is arranged in the box, a matched press roller is arranged in the channel, a back end of the press roll is fixedly connected with a front end of a first rotating rod, a back end of the first rotating rod is rotationally connected with a first bearing, the first bearing is fixedly connected to the middle of a front side of a longitudinal support plate, a first bevel gear is arranged in the middle of the first bearing, a rubber rod is fixedly connected to a lower end of the longitudinal support plate, a spring is arranged in the rubber rod, a support block is arranged at a lower end of the rubber rod, the feeding area is arranged at an upper left end of the inside of the box, and a control panel is arranged on an outer side of the box. The composite production device is simple in structure, can produce products at different thicknesses while greatly improving the product quality, conforms to reality, and is high in practicability and suitable for promotion.