The invention relates to an intelligent cooling method for transformer substation main transformer ultrasonic waves. The intelligent cooling method comprises the following steps: carrying out programming by a control module; after the operation of a main transformer, turning on an intelligent cooling device for transformer substation main transformer ultrasonic waves; when a temperature detector detects that the oil temperature of transformer oil is increased to a high temperature threshold value, controlling to turn on an ultrasonic generator automatically by the control module, and transmitting ultrasonic waves to carry out ultrasonic oscillation on transformer oil inside the main transformer by a surround ultrasonic transmitting probe; when the oil temperature of the transformer oil isincreased continuously, increasing the power of the ultrasonic waves generated by the ultrasonic generator, and vice versa; when the oil temperature of the transformer oil is decreased to a set value,automatically turning off the ultrasonic generator; monitoring an electric field disturbance condition generated by the transformer oil inside the main transformer by the surround electric field monitoring probe of an electric field monitor, and when electric field disturbance reaches a set value, automatically controlling and reducing the power of ultrasonic waves generated by the ultrasonic generator by the control module. According to the intelligent cooling method, the heat exchange and heat dissipation cooling capacity can be strengthened efficiently.