The invention relates to an anti-fake marker and in particular relates to a variable partial holographic logic corresponding information anti-fake marker and a manufacturing method thereof. The anti-fake marker comprises a plastic membrane layer, a two-dimensional code printing layer, a permanent mold pressing information layer, a positioning mold pressing layer, a color layer and an adhesive layer which are arranged in sequence from top to bottom, wherein a partial hollow printing layer and a partial aluminum plating layer are sequentially arranged below the positioning mold pressing layer; the partial hollow printing layer and the partial aluminum plating layer respectively comprise a part of variable information and form complete variable information after being combined; a two-dimensional code of the two-dimensional code printing layer has a corresponding relationship with the variable information; the variable information is a variable graphic diagram and/or variable digits; and an invisible ink layer is arranged below the partial aluminum plating layer correspondingly. With the combination of holographic patterns and printing patterns, the variable information has a holographic alumite effect, the two-dimensional code has the corresponding relationship with the variable information, and is not easy to imitate, simple to identify, good in anti-fake effect and high in anti-transferring property, and the manufacturing method of the anti-fake marker is scientific and reasonable and simple and feasible.