基本信息:
- 专利标题： 一种三甲基丙酮酸的合成方法
- 专利标题（英）：Method for synthesizing trimethylpyruvic acid
- 申请号：CN201811611906.1 申请日：2018-12-27
- 公开(公告)号：CN109796322A 公开(公告)日：2019-05-24
- 发明人： 高仰哲 , 吴法浩 , 李钢
- 申请人： 南京红杉生物科技有限公司
- 申请人地址： 江苏省南京市栖霞区纬地路9号F6栋202室
- 专利权人： 南京红杉生物科技有限公司
- 当前专利权人： 南京红杉生物科技有限公司
- 当前专利权人地址： 江苏省南京市栖霞区纬地路9号F6栋202室
- 代理机构： 北京科家知识产权代理事务所
- 代理人： 陈娟
- 主分类号： C07C51/02
- IPC分类号： C07C51/02 ; C07C59/185
The invention belongs to the field of drug synthesis, and discloses a method for synthesizing trimethylacetic acid. Process reactions of the method are all conventional operation, equipment is simple,copper sulfate with the moderate oxidizing capability is selected as an oxidant, and the problems are solved that the purity of a product is reduced when trimethylacetic acid with properties similarto those of the product is generated due to the excessively-high oxidizing capability and excessive oxidation of a potassium permanganate oxidant, the yield is low due to excessively-poor oxidizing capability of a sodium hypochlorite oxidant, and a lot of waste water is generated. The chemical purity of a final product can reach 99.5 or above, the yield can reach 93.7 or above, and the final product has a good industrial prospect.