The invention discloses an uncoupling rod tripping prevention device and method and a locomotive vehicle, and solves the problems that upper tripping false operation risks are still present, a structure is complicated, and operations are inconvenient in the prior art. The device has the advantages that separation of hooks of mutually connected locomotive vehicles caused by excessive tripping falseoperations of an uncoupling rod can be prevented, operations are simple, and the device is safe and reliable in the running process of the locomotive vehicle. The technical scheme includes that the device comprises an uncoupling rod seat, a tripping prevention component is arranged on one side of the uncoupling rod seat and comprises a tripping prevention blocking portion and a lifting and pulling portion, the tripping prevention blocking portion is used for limiting tripping of the uncoupling rod, the lifting and pulling portion is fixedly connected with the tripping prevention blocking portion and penetrates the uncoupling rod seat and is connected with an elastic portion, the tripping prevention blocking portion can overcome resistance of the elastic portion by operating the lifting and pulling portion, and a working state is changed.