
基本信息:
- 专利标题: c-MET激动型抗体及其用途
- 专利标题(英):c-MET agonistic antibody and use thereof
- 申请号:CN201711116927.1 申请日:2017-11-13
- 公开(公告)号:CN109771642A 公开(公告)日:2019-05-21
- 发明人: 房健民 , 蒋明 , 尹衍新 , 郭佳 , 于丽华
- 申请人: 同济大学苏州研究院
- 申请人地址: 江苏省苏州市吴中区金枫南路198号
- 专利权人: 同济大学苏州研究院
- 当前专利权人: 同济大学苏州研究院
- 当前专利权人地址: 江苏省苏州市吴中区金枫南路198号
- 代理机构: 北京集佳知识产权代理有限公司
- 代理人: 彭鲲鹏; 韩宏星
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61P9/10 ; C07K16/28 ; G01N33/50 ; A61K45/06
The invention relates to a c-MET agonistic antibody and a use thereof, which belong to the technical filed of a medicine. The present invention provides the use of a c-MET agonist for preparation of amedicine for treatment or prevention of a vascular endothelial cell injury disease, in particular for the medicine for cerebral infarction or myocardial infarction. The invention also relates to a specific c-MET agonist. The c-MET agonist of the present invention can effectively promote the repair of vascular endothelial cell damage and is useful for treating ischemic diseases and blood-brain barrier-damaging diseases. The c-MET agonist in the present invention is preferably a c-MET agonistic antibody. The invention further relates to a pharmaceutical composition comprising the c-MET agonist.
公开/授权文献:
- CN109771642B c-MET激动型抗体及其用途 公开/授权日:2022-09-20
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K39/00 | 含有抗原或抗体的医药配制品 |
--------A61K39/395 | .抗体;免疫球蛋白;免疫血清,例如抗淋巴细胞血清 |