![一种抗PRRSV感染的猪源miR-c89及其应用](/CN/2018/1/316/images/201811583181.jpg)
基本信息:
- 专利标题: 一种抗PRRSV感染的猪源miR-c89及其应用
- 专利标题(英):Swine-origin miR-c89 capable of resisting PRRSV (Porcine reproductive and respiratory syndrome virus) infection, and application thereof
- 申请号:CN201811583181.X 申请日:2018-12-24
- 公开(公告)号:CN109679952A 公开(公告)日:2019-04-26
- 发明人: 肖书奇 , 李爽 , 闫云欢 , 张晓彬
- 申请人: 西北农林科技大学
- 申请人地址: 陕西省西安市杨凌示范区邰城路3号
- 专利权人: 西北农林科技大学
- 当前专利权人: 西北农林科技大学
- 当前专利权人地址: 陕西省西安市杨凌示范区邰城路3号
- 代理机构: 北京慕达星云知识产权代理事务所
- 代理人: 李冉
- 主分类号: C12N15/113
- IPC分类号: C12N15/113 ; A61K31/713 ; A61P31/14
The invention discloses a swine-origin miR-c89 capable of resisting PRRSV (Porcine reproductive and respiratory syndrome virus) infection. Through RT-qPCR (Real Time-quantitative Polymerase Chain Reaction), TCID50 (Tissue Culture Infectious Dose 50) and western blot methods, miR-c89 derived from swine coding is proved to obviously inhibit the replication and the proliferation of high pathogenicityand low pathogenicity PRRSV for the first time, the micoRNA is hopefully developed into a novel medicine capable of preventing and curing porcine reproductive and respiratory syndrome and used for researching the gene-modified pig capable of resisting the porcine reproductive and respiratory syndrome, and a foundation is laid for the prevention and control of the PRRSV.
公开/授权文献:
- CN109679952B 一种抗PRRSV感染的猪源miR-c89及其应用 公开/授权日:2022-04-15