The invention belongs to the technical field of environment-friendly novel materials and relates to a nano composite environment-friendly oxygen-resistant pipe preparation method. A nano composite environment-friendly oxygen-resistant pipe prepared according to the method makes use of nano titanium dioxide for inhibiting aquatic reproduction, nano titanium dioxide has excellent antibacterial and harmful gas eliminating performances, and material intrinsic or external harmful gases can be adsorbed and decomposed to reduce harms to human bodies. Graphene is great in thermal conductivity and mechanical performance, and a compact graphene crystallized film is formed on the pipe surface after graphene glue solution soaking, so that oxygen and moisture can be blocked; in addition, graphene is hydrophobic intrinsically, and moisture isolation is further promoted. By isolation of oxygen and moisture through the graphene crystallized film, oxygen-resistant effect declining caused by moisture infiltration can be prevented. Due to doping of nano titanium dioxide into pipes, strength and aging resistance of the pipes can be improved, and service lives of the pipes are greatly prolonged.