基本信息:
- 专利标题： 一种醋酸阿比特龙片剂的药物组合物及其制备方法
- 专利标题（英）：Abiraterone acetate tablet medicine composition and preparation method thereof
- 申请号：CN201710466293.6 申请日：2017-06-19
- 公开(公告)号：CN109125276A 公开(公告)日：2019-01-04
- 发明人： 赵娜娜 , 郑晓清 , 杨清敏 , 汪文化 , 张明会
- 申请人： 齐鲁制药有限公司
- 申请人地址： 山东省济南市高新区新泺大街317号
- 专利权人： 齐鲁制药有限公司
- 当前专利权人： 齐鲁制药有限公司
- 当前专利权人地址： 山东省济南市高新区新泺大街317号
- 主分类号： A61K9/20
- IPC分类号： A61K9/20 ; A61K31/58 ; A61K47/32 ; A61P35/00 ; A61K9/14
The invention relates to an abiraterone acetate tablet medicine composition and a preparation method thereof, and belongs to the technical field of medicine preparations. According to an abiraterone acetate tablet, firstly, a hot melting extruding technology is adopted for preparing a solid dispersion body of abiraterone acetate and copovidone, then the solid dispersion body, a diluent, an adhesive, a disintegrating agent and a lubricating agent are prepared into a mixture, and finally the mixture is prepared into tables. The prepared abiraterone acetate tablets improve the dissolution rate and bioavailability of a peroral solid preparation and have larger clinic application value; in addition, the prepared abiraterone acetate tablets are stable in quality, controllable and convenient to conduct industrialized production.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K9/00 | 以特殊物理形状为特征的医药配制品 |
| --------A61K9/20 | .丸剂、锭剂或片剂 |