The invention discloses a production process of high-quality sodium thiocyanate and belongs to the technical field of compound production. The production process comprises the following steps: A, introducing air or oxygen into an ammonia-soda process coking desulfuration waste liquid, and performing oxidation treatment on the waste liquid; B, decoloring the material liquid oxidized in the step A;C, putting sodium hydroxide into the material liquid decolored in the step B, and carrying out ammonia removal treatment; D, cooling the material liquid after ammonia removal treatment in the step C,keeping the temperature to carry out crystal separation, and filtering to obtain a sodium thiocyanate solution; E, filtering the cooled sodium thiocyanate solution after crystal separation by using anano filter membrane filtering system; F, concentrating the clear liquid obtained in the step E, cooling, carrying out centrifugation to obtain a sodium thiocyanate wet product, and drying the wet product, thereby obtaining a sodium thiocyanate product, wherein the centrifugation mother liquid is fed back to the step E for treatment. The production process disclosed by the invention is simple to operate, easy to control and stable in production process, the obtained sodium thiocyanate is high in quality and high in yield, and byproducts ammonia water and mirabilite are generated.