The invention discloses a biopharmaceutical stirring device which comprises a casing. The casing is a cavity structure, the top opening of the casing is provided with a cover plate, one side of the inner wall of the casing is provided with a fixing rod, the other side of the fixing rod is provided with an oscillating mechanism, and the oscillating mechanism comprises a limiting ring. The two endsof the limiting ring are respectively symmetrically provided with a fixed block I and a fixed block II. A shaft sleeve I is inserted in the intermediate position of the fixed block I, a shaft sleeve II is inserted in the other end of the fixed block II, the bottom end of the shaft sleeve I and the top end of the shaft sleeve II are inserted into the two ends of the limiting ring, a movable rod isinserted between the shaft sleeve I and the shaft sleeve II, and a fixing bracket is arranged on the movable rod and inside the limiting ring. The biopharmaceutical stirring device has the advantagesthat raw materials are oscillated up and down in the biopharmaceutical stirring device, up and down movement can also occur when mixed slurry is rotated circumferentially, the stirring efficiency of the device can be improved, the raw materials can be mixed more uniformly, and quality and production efficiency of biopharmaceuticals can be improved.