The invention discloses a drive shaft assembly of a screw drilling tool, and relates to the field of oil drilling. The drive shaft assembly comprises a drive shaft housing, a drive shaft is installedin the drive shaft housing in a penetrating mode. The drive shaft is sequentially provided with an upper radial moving bearing, a thrust bearing set, an anti-drop device, a lower radial bearing movingsleeve and a stopping ring from top to bottom. An upper radial static bearing is arranged between the upper radial moving bearing and the drive shaft housing. A lower radial bearing static sleeve isarranged between the lower radial bearing moving sleeve and the drive shaft housing. Three protruding spiral centralizer belts are evenly arranged on the drive shaft housing and disposed along the outer circumferential surface of a drive shaft housing body, and abrasion resistance layers are arranged on the outer circular surfaces of the spiral centralizer belts. The drive shaft assembly of the screw drilling tool has a simple structure, and reduces the frequency of replacing the radial bearings, the abrasion resistance layers are welded to the surfaces of the spiral centralizer belts of the drive shaft housing body in a spreading mode, the abrasion speed of the centralizer belts is reduced, and the life of the drive shaft housing is prolonged.