The invention discloses an efficient medicine powder mixing machine and relates to the field of pharmaceutical production equipment. The efficient medicine powder mixing machine comprises a rack, a material mixing tank, a material mixing mechanism and an air blowing disc, wherein the material mixing tank is fixedly mounted on the rack; the material mixing mechanism is composed of a driving motor,a rotary shaft and a stirring spiral belt; the driving motor is fixedly mounted at the side end of the rack; the rotary shaft is fixedly connected with an output shaft of the driving motor; the rotaryshaft is in rotary connection with the material mixing tank; the stirring spiral belt is fixedly mounted on the rotary shaft through a screw; the stirring spiral belt is located in the material mixing tank; the air blowing disc is fixedly mounted at the side end of the rack; an air inlet flange pipe is arranged at the central position of one end face of the air blowing disc; four air spraying nozzles are uniformly arranged on the other end face of the air blowing disc; the four air spraying nozzles are communicated with the air inlet flange pipe. The mixing material machine is used for mixingmedicine powder through a mechanical manner and a pneumatic manner; the mixing efficiency is higher and the mixing time is saved.