基本信息:
- 专利标题： 一种包覆型羧基化SiO2荧光纳米球的制备方法
- 专利标题（英）：Preparation method of coating type chloracetylated SiO2 fluorescent nanosphere
- 申请号：CN201810135759.9 申请日：2018-02-09
- 公开(公告)号：CN108192596A 公开(公告)日：2018-06-22
- 发明人： 刘清浩 , 郭金春 , 李瑞芳 , 刘红彦 , 胡志勇
- 申请人： 中北大学
- 申请人地址： 山西省太原市学院路3号
- 专利权人： 中北大学
- 当前专利权人： 中北大学
- 当前专利权人地址： 山西省太原市学院路3号
- 代理机构： 太原华弈知识产权代理事务所
- 代理人： 李毅
- 主分类号： C09K11/02
- IPC分类号： C09K11/02 ; C09K11/06 ; C09K11/59 ; C09B57/02 ; C09B57/00 ; B82Y30/00 ; B82Y40/00
The invention discloses a preparation method of a coating type chloracetylated SiO2 fluorescent nanosphere. A double-bond allyl fluorescent probe, methacrylic acid and a silane coupling agent KH151 are used as raw materials; polyreaction is performed to obtain a fluorescent polymer; through the effect of chemical bonds, the fluorescent polymer is grafted onto the surface of an SiO2 nanosphere so as to obtain the coating type chloracetylated SiO2 fluorescent nanosphere through preparation. The prepared coating type chloracetylated SiO2 fluorescent nanosphere has the advantages that the morphostructure is stable; the monodispersity is good; the luminous efficiency is high; the biocompatibility is high; the carboxylation functional groups are realized; the firm -Si-O-Si- bond also exists; theproduct fluorescence leakage and quenching are avoided.
公开/授权文献:
- CN108192596B 一种包覆型羧基化SiO2荧光纳米球的制备方法 公开/授权日：2020-07-24