基本信息:
- 专利标题： SD大鼠赫特维希上皮根鞘细胞系HERS-H1和HERS-C2及建立方法及应用
- 专利标题（英）：Hertwig's epithelial root sheath cell lines HERS-H1 and HERS-C2 of SD rats as well as establishing method and applications of Hertwig's epithelial root sheath cell lines HERS-H1 and HERS-C2
- 申请号：CN201711205709.5 申请日：2017-11-27
- 公开(公告)号：CN108048403A 公开(公告)日：2018-05-18
- 发明人： 陈国庆 , 田卫东 , 李雪冰
- 申请人： 四川大学
- 申请人地址： 四川省成都市武侯区一环路南一段24号
- 专利权人： 四川大学
- 当前专利权人： 四川大学
- 当前专利权人地址： 四川省成都市武侯区一环路南一段24号
- 代理机构： 成都九鼎天元知识产权代理有限公司
- 代理人： 易小艺
- 主分类号： C12N5/10
- IPC分类号： C12N5/10 ; C12N15/867 ; A61L27/38 ; C12R1/89
The invention belongs to the field of biotechnology, and relates to an establishing method of Hertwig's epithelial root sheath cell lines HERS-H1 and HERS-C2 of SD rats and applications of the Hertwig's epithelial root sheath cell lines HERS-H1 and HERS-C2 of SD rats in tooth regeneration. The establishing method and the applications are characterized in that the Hertwig's epithelial root sheath cell line HERS-H1 is assigned with the accession number of CCTCC NO.C2017249, and the Hertwig's epithelial root sheath cell line HERS-C2 is assigned with the accession number of CCTCC NO.C2017250. According to the method and the applications, for the cell lines, the features of the primary Hertwig's epithelial root sheath cells in the tooth development process are reserved, passage to 50 generations is available at least, and the multiplication rate is greatly improved compared with that of the primary cells. The establishing method is easy to operate, and high in stability and repeatability.
公开/授权文献:
- CN108048403B SD大鼠赫特维希上皮根鞘细胞系HERS-H1和HERS-C2及建立方法及应用 公开/授权日：2021-02-19