The invention provides a laser connection method for high-strength metallurgical bonding of titanium-aluminum dissimilar metals. The method comprises the following steps: firstly, separately arrangingtwo protruding platforms along the thickness direction of a welding part and on two butting surfaces of an I-shaped joint for a to-be-welded test piece joint, wherein the two platforms are equal in length in the length direction and width direction; the height sum in the thickness direction is equal to the thickness of a butted test plate; secondly, performing before-welding treatment and optimizing laser welding parameters to finish first welding-brazing; and afterwards, performing second modified welding at a titanium side adjacent to welding-brazing beads, wherein the two welding beads areclose to each other but are not intersected with each other. The connection method provided by the invention can be used for performing the second welding by the side of the welding-brazing bead adjacent to the high-melting-point titanium side by utilizing the characteristic that dissimilar metals have high melting point differences; a titanium-aluminum bonding interface is re-melted and modifiedby a temperature field of the second welding, so the phase structure at the bonding interface is optimized and the brittleness of a joint is weakened; and meanwhile a special joint structure is adopted to improve the bonding strength of the root part of the welding bead and improve the reliability of the joint.