基本信息:
- 专利标题： 一种连续制备4-(6-羟基己氧基)苯酚的方法
- 专利标题（英）：Method for continuously preparing 4-(6-hydroxyhexyloxy)phenol
- 申请号：CN201610847687.1 申请日：2016-09-23
- 公开(公告)号：CN107867979A 公开(公告)日：2018-04-03
- 发明人： 陈光文 , 李雷 , 周峰 , 焦凤军 , 韩梅
- 申请人： 中国科学院大连化学物理研究所
- 申请人地址： 辽宁省大连市沙河口区中山路457-41号
- 专利权人： 中国科学院大连化学物理研究所
- 当前专利权人： 中国科学院大连化学物理研究所
- 当前专利权人地址： 辽宁省大连市沙河口区中山路457-41号
- 代理机构： 沈阳科苑专利商标代理有限公司
- 代理人： 马驰
- 主分类号： C07C41/16
- IPC分类号： C07C41/16 ; C07C41/34 ; C07C43/23 ; B01J19/00
The invention discloses a method for continuously preparing 4-(6-hydroxyhexyloxy)phenol in a micro-reactor. The method comprises the following steps: dissoling hydroquinone and 6-chloro-1-hexanol in the solvent ethanol; and with an alkali aqueous solution of NaOH<-> as a catalyst, carrying out a bimolecular nucleophilic substitution reaction in the micro-reactor so as to continuously prepare 4-(6-hydroxyhexyloxy)phenol. Compared with the prior art, the method provided by the invention has the following advantages that the synthesis time of 4-(6-hydroxyhexyloxy)phenol is reduced to 10 min or less from original 20 hours; yield is increased from original 40% to 80%;continuous operation during the reaction can be realized; and integration and enlargement can be easily realized.
公开/授权文献:
- CN107867979B 一种连续制备4-(6-羟基己氧基)苯酚的方法 公开/授权日：2020-10-30