The invention discloses a drill bit fixture with an adjustable drilling direction. The drill bit fixture comprises a bearing plate (3) and a base (1) fixedly connected to a workbench of a drilling machine, wherein a rotary shaft (2) and a hydraulic cylinder (5) are arranged on the base (1); a shaft sleeve (4) is arranged at one end of the bearing plate (3); the shaft sleeve (4) is arranged on therotary shaft (2) in a sleeving manner; the other end of the bearing plate (3) is hinged to the top end of a telescopic rod of the hydraulic cylinder (5); and a three-jaw chuck (6) is installed on thebearing plate (3). According to the drill bit fixture disclosed by the invention, multiple installation and detachment between a traditional drill bit fixture and a workbench of a drilling machine areavoided through adjusting the included angle between the axis of a drill bit and the plane of the workbench of the drilling machine, so that drilling in the end surface of a working end of the drillbit is facilitated.