The invention belongs to the technical field of fish feed and particularly relates to feed for enhancing immunocompetence of snakehead. The feed is prepared from raw materials in parts by weight as follows: 36-40 parts of chicken skeleton, 70-75 parts of corn, 55-60 parts of sorghum, 42-46 parts of peanut meal, 15-17 parts of fresh garlic straw, 18-20 parts of fresh sweet potato stems, 8-9 parts of purple sweet potatoes, 11-12 parts of fresh dragon fruit peels, 0.24-0.26 parts of hawthorn polysaccharides and 3.2-3.8 parts of a feed additive. The feed can effectively activate the immune systemof a fish body, enhance the capability of the body for resisting germs and viruses, inhibit pathogenic microorganisms, effectively improve the serum enzyme activity of the snakehead, scavenge free radical, improve the oxidation resistance, effectively reduce diseases, enhance the intake capability, improve the growth and development capability of the body, increase the feed conversion rate, has abetter protection function on the liver of the snakehead, enhance the detoxification capability of the liver and the nutritional substance conversion capability, promote growth and improve the quality.