The invention discloses a domestic single-stage air purification device. The domestic single-stage air purification device comprises an air inlet pipe communicating with the outdoor atmospheric environment, an air outlet pipe communicating with the indoor temperature, a purification tank arranged between the air inlet pipe and the air outlet pipe and internally provided with alkaline liquid, a dehumidifying device and a disinfection and sterilization device. The air inlet pipe communicates with the purification tank. The air inlet end of the air inlet pipe is provided with a gauze filter. Theair outlet end of the purification tank communicates with the dehumidifying device and the disinfection and sterilization device through a connecting pipeline in sequence. An exhaust fan is arranged on the connecting pipeline between the purification tank and the dehumidifying device. The disinfection and sterilization device is connected with the air outlet pipe. The domestic single-stage air purification device brings fresh air to people and is good for physical and psychological health of people.