![一种丙酮高选择性氯化制备1,1,3-三氯丙酮的方法](/CN/2017/1/176/images/201710882012.jpg)
基本信息:
- 专利标题: 一种丙酮高选择性氯化制备1,1,3-三氯丙酮的方法
- 专利标题(英):Method for preparing 1,1,3-trichloroacetone through high-selectivity chlorination of acetone
- 申请号:CN201710882012.5 申请日:2017-09-26
- 公开(公告)号:CN107602364A 公开(公告)日:2018-01-19
- 发明人: 王红伟 , 王佳 , 傅胜辉 , 杨红军 , 张明祥 , 陈军 , 谢珊
- 申请人: 安徽国星生物化学有限公司
- 申请人地址: 安徽省马鞍山市当涂经济开发区红太阳生命科学工业园
- 专利权人: 安徽国星生物化学有限公司
- 当前专利权人: 安徽国星生物化学有限公司
- 当前专利权人地址: 安徽省马鞍山市当涂经济开发区红太阳生命科学工业园
- 代理机构: 合肥顺超知识产权代理事务所
- 代理人: 马娇娇
- 主分类号: C07C45/63
- IPC分类号: C07C45/63 ; C07C49/16
The invention relates to the technical field of synthesis of a folic acid intermediate, in particular to a method for preparing 1,1,3-trichloroacetone through high-selectivity chlorination of acetone.The method comprises the process steps as follows: firstly, acetone is taken as a raw material and subjected to staged catalytic chlorination of chlorine, an amine compound is taken as a catalyst tochlorinate acetone to a dichloroacetone stage, then, an alcohol compound is added to serve as a solvent, water is added to adjust the reaction process, 1,1,3-trichloroacetone is prepared through deepchlorination, and the yield of the method is up to 90% or above. With the adoption of the technical scheme, the defects that existing preparation methods for 1,1,3-trichloroacetone have poorer synthesis technological level, low preparation efficiency and complex operation process and obtained products are low in selectivity can improved to a certain extent.
公开/授权文献:
- CN107602364B 一种丙酮氯化制备1,1,3-三氯丙酮的方法 公开/授权日:2020-06-05