The invention discloses a method capable of improving the adipose survival rate and regeneration of the adipose tissue. The method includes the steps of extracting preadipocyte, transplanting adipocyte, extracting nutrient components and conducting backfill transplantation. According to the method capable of improving the adipose survival rate and regeneration of the adipose tissue, obtained adipocyte can continue to differentiate into cells of the adipose tissue after being transplanted, and the problem of transportation absorption activity of traditional adipocyte and the problem of adipocyte transplantation absorption or necrosis and the like are solved; the transplanted adipocyte can stably and enduringly survive for a long time. According to the method capable of improving the adipose survival rate and regeneration of the adipose tissue, extracted materials are converted into adipocyte after being transplanted, the situation can be promoted that original adipocyte continues to grow and finally becomes the adipose tissue stably, and the survival rate reaches 90%. Activated preadipocyte are converted into adipocyte, the adipose tissue of a part which needs to be filled is formed, the situation is promoted that original adipocyte continues to grow, vessel forming can be facilitated, vascularization and re-survive of the transplanted adipocyte can be accelerated, angiopoiesis promotion factors can be released, therefore, the transplanted adipose can rapidly survive and become normal adipose tissue with vital force, and patients' senses of body beauty can be significantly improved.