The invention belongs to the field of sandstone-type uranium ore exploration, and specifically discloses an outlining method for an in-situ leaching sandstone-type uranium-bearing basin favorable mineralization section. The method comprises the steps: determining a research area, and selecting a target layer; collecting a land surface sample of a bottom plate of a basin edge target layer, a drilled coal stone sample or a carbon mudstone sample; collecting sandstone samples of the above samples at the same layer; carrying out the vitrinite reflectance measurement of the collected coal stone sample or the collected carbon mudstone sample, and calculating the maximum burial depth of an ore-containing target layer; selecting apatite minerals from the collected mudstone sample, carrying out the fission-track dating of apatite, and carrying out the inversion of the relation between temperature and time in construction evolution; verifying whether the above inversion result is matched with the actual condition or not: extracting the measurement result if the above inversion result is matched with the actual condition, or else checking whether the sampling is standard or not; drawing an erosion thickness contour map in the research area according to an erosion thickness calculation result, carrying out the research of restriction of construction uplift erosion on uranium mineralization, and outlining a favorable mineralization section. The method is clear in sampling object, is clear in analysis flow, and is simple in operation.