The invention discloses a visual pipeline interior cleaning device. The visual pipeline interior cleaning device comprises a hollow guide pipe, a barrier isolating structure, a cleaning structure and a pumping drainage device, wherein one end of the hollow guide pipe is arranged inside a micro pipeline, and the other end of the hollow guide pipe is arranged on the outer portion of the micro pipeline; the barrier isolating structure is arranged at the end, inside the micro pipeline, of the hollow guide pipe, and the barrier isolating structure can penetrate through a barrier and isolate the barrier into a set interval of the micro pipeline; the cleaning structure comprises a spraying part extending out of the hollow guide pipe and used for spraying liquid to clean the micro pipeline; and the pumping drainage device is connected with the hollow guide pipe and used for pumping the barrier after cleaning. The visual pipeline interior cleaning device can improve the effect of cleaning of the micro pipeline and simplify the difficulty of cleaning of the micro pipeline.