The invention relates to a safety monitoring and control device for the interior environment of a vehicle. The safety monitoring and control device comprises a main controller, an alcohol sensor circuit, a carbon monoxide sensor circuit, a pyroelectric infrared sensing circuit, a storage circuit, a key circuit, a liquid crystal display, a power supply control driving circuit and a skylight control driving circuit; the output end of the alcohol sensor circuit, the output end of the carbon monoxide sensor circuit, the output end of the pyroelectric infrared sensing circuit and the output end of the key circuit are connected with the corresponding input ends of the main controller respectively, and the storage circuit and the main controller are in bidirectional connection; the three output ends of the main controller are connected with the input end the liquid crystal display, the input end of the power supply control driving circuit and the input end of the skylight control driving circuit respectively, the output end of the power supply control driving circuit is connected with the input end of a vehicle power supply loop, and the output end of the skylight control driving circuit is connected with the input end of a vehicle skylight opening control loop. The safety monitoring and control device for the interior environment of the vehicle is conductive to improving the interior air environment, and the safety factor of personnel in the vehicle is effectively increased.