
基本信息:
- 专利标题: 医药中间体羰基取代芳基硫醚化合物的合成方法
- 专利标题(英):Compounding method of medical intermediate carbonyl-substituted aryl thioether compound
- 申请号:CN201710215221.4 申请日:2015-10-08
- 公开(公告)号:CN106986799A 公开(公告)日:2017-07-28
- 发明人: 不公告发明人
- 申请人: 钱小英
- 申请人地址: 江苏省常州市新北区凤凰名城26栋301室
- 专利权人: 钱小英
- 当前专利权人: 钱小英
- 当前专利权人地址: 江苏省常州市新北区凤凰名城26栋301室
- 主分类号: C07C319/14
- IPC分类号: C07C319/14 ; C07C323/22
The invention relates to a compounding method of a medical intermediate carbonyl-substituted aryl thioether compound. The method includes that a formula-(1) compound reacts with a formula-(II) compound in organic solvent with the presence of catalysts, organic ligands, activators and alkali at the nitrogen atmosphere, and a formula-(III) compound is obtained through post-treatment after reaction, wherein each R1 is C1-C6 alkyl independently, R2 is C1-C6 alkyl, C1-C6 alkoxy, halogen or nitryl, and X is halogen. The compounding method of the carbonyl-substituted aryl thioether compound has the advantages that a novel composite reaction system is adopted, and the target product can be obtained at high yield through comprehensive selection of the catalysts, the organic ligands, the activators, the alkali and the organic solvent; the reaction process is moderate, needs of the fields such as chemical engineering and medicine are met, and market prospect is wide.
IPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07C | 无环或碳环化合物 |
------C07C319/00 | 硫醇、硫醚、氢化多硫化物或多硫化物的制备 |
--------C07C319/14 | .硫醚的 |