The invention provides a wire clamping device to solve the problem that a wire can be damaged when being directly clamped through a chuck in the prior art. The wire clamping device comprises a clamping body. The clamping body comprises at least two clamping blocks, wherein one of the clamping blocks is used for being clamped and fixed through a chuck, and all the clamping blocks are provided with clamping end faces used for being matched for clamping. The clamping body further comprises a wire clamping hole stretching across the clamping end faces of all the clamping blocks. The wire clamping hole stretches across the clamping end faces of all the clamping blocks, during use, the wire clamping hole is defined by the clamping blocks so that the wire can be clamped in the wire clamping hole, the wire is clamped in the round clamping hole and cannot deform or be damaged; and at least clamping block is clamped by the chuck so that the clamping body formed by the clamping blocks can be clamped in the chuck, the wire can be clamped, and meanwhile the clamping body clamping the wire is clamped in the chuck.