The invention discloses a low-noise airflow cotton mixing machine. The low-noise airflow cotton mixing machine comprises a rotating head, a high-pressure air pipe and a machine frame, a lower dehumidification layer is arranged on the outer layer of the bottom of the machine frame, a low noise-insulation layer is arranged on the outer layer of the lower dehumidification layer, an upper dehumidification layer is arranged on the outer layer of the top of the machine frame, an upper noise-insulation layer is arranged on the outer layer of the upper dehumidification layer, an operation indicator lamp is arranged on the upper noise-insulation layer, a roller is arranged inside the machine frame, the two ends of the roller are connected with the machine frame, sprayers are arranged at the lower end of the inner side of the machine frame, sprayer holes are formed in the sprayers, sprayer nets are arranged on the sprayer holes, the rear ends of the sprayers are connected with an air-guiding pipe, conveying pipelines are arranged at the two ends of the machine frame, a rotating head is arranged inside the machine frame, rotating air holes are formed in the rotating head, the right end of the rotating head is connected with the high-pressure air pipe, high-pressure air holes are formed in the high-pressure air pipe, and a motor is arranged at the right end of the outer side of the machine frame. The machine has the advantages of being high in reliability, compact in structure, high in mixing efficiency and even in fiber mixing, and being provided with few motion components.