The invention discloses a high-temperature-resisting signal cable, which comprises an external wrapping wire and a plurality of wire cores arranged inside the external wrapping wire, wherein filler is arranged among the external wrapping wire and the wire cores, the external wrapping wire is sequentially provided with a radiation crosslinked ethylene-tetrafluoroethylene sheath, a nickel-plated copper wire braiding layer and a wrapping layer from outside to inside, and each wire core is sequentially provided with an insulating layer and fifth nickel-plated soft copper conductors from outside to inside. The high-temperature-resisting signal cable has excellent mechanical, electrical and radiation-resistant properties, the tensile strength thereof can be up to 40 MPa or more, the high-temperature-resisting signal cable is highly wear-resistant, bend resistant and stress cracking resistant, generally has no impurity, gas evaporation and the like at low air pressure, namely, has good outgassing property, thus cannot contaminate other components in equipment, has excellent chemical stability, and is resistant to various oil and liquid.