![制备3‑氰基‑4‑异丙氧基苯甲酸的方法](/CN/2016/1/244/images/201611221183.jpg)
基本信息:
- 专利标题: 制备3‑氰基‑4‑异丙氧基苯甲酸的方法
- 专利标题(英):Method for preparing 3-cyano-4-isopropoxybenzoic acid
- 申请号:CN201611221183.5 申请日:2016-12-27
- 公开(公告)号:CN106674044A 公开(公告)日:2017-05-17
- 发明人: 池永贵 , 黄轩
- 申请人: 苏州山青竹生物医药有限公司
- 申请人地址: 江苏省苏州市常熟经济技术开发区生态园路8号1幢
- 专利权人: 苏州山青竹生物医药有限公司
- 当前专利权人: 苏州山青竹生物医药有限公司
- 当前专利权人地址: 江苏省苏州市常熟经济技术开发区生态园路8号1幢
- 主分类号: C07C253/30
- IPC分类号: C07C253/30 ; C07C255/57
The invention discloses a method for preparing 3-cyano-4-isopropoxybenzoic acid. A first step, 3-formyl-4-methyl hydroxybenzoate is prepared with methyl parahydroxybenzoate; a second step, 3-cyano-4-methyl hydroxybenzoate is prepared with the 3-formyl-4-methyl hydroxybenzoate; a third step, 3-cyano-4-methyl isopropoxybenzoate is prepared with the 3-cyano-4-methyl hydroxybenzoate; a fourth step, the 3-cyano-4-isopropoxybenzoic acid is prepared with the 3-cyano-4-methyl isopropoxybenzoate. The preparation method of the 3-cyano-4-isopropoxybenzoic acid, which is provided by the invention, has the advantages that 1) the use of the cuprous cyanide of hypertoxic cyanide in a previous process is avoided, and the method is more suitable for industrialization; 2) cyano is prepared by formyl, and the method is high-efficiency and direct, and is suitable for quantity production; 3) all raw materials are cheap and easily obtained, and the cost advantage is obvious.
IPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07C | 无环或碳环化合物 |
------C07C253/00 | 羧酸腈的制备 |
--------C07C253/30 | .由不涉及形成氰基的反应 |