The invention provides an active-standby signal processing method of an LTE base station baseband processing board. There is a group of active-standby state signals between active and standby BPUs, and the signals comprise a board card in-place signal, an active-standby state signal and a heartbeat signal, when the standby BPU detects that the active BPU is not in place or is switched to the standby BPU or the heartbeat is overtime, the standby BPU immediately sets itself as the active BPU and sets the opposite terminal BPU as the standby BPU at the same time so as to accomplish the active-standby switch of the BPUs, and active-standby state synchronization and DSP beat synchronization are accomplished at the same time. By adoption of the active-standby signal processing method provided by the invention, the synchronization of upper layer configuration parameters during the switch of the active and standby BPUs is not only solved, the synchronization of massive user data, control data, physical layer data and link layer data is also solved, during the switch of the active and standby BPUs, the original business is not interrupted, instant switch is realized, no user perception is realized as well.