The invention discloses pipe inner wall cleaning equipment which comprises a base, a motor, a stand column, a rotating shaft and a cleaning device. The cleaning device comprises connection discs and connection rods. The connection discs are arranged on the rotating shaft in a sleeved manner. Each connection rod comprises a fixing plate and a guide rod, and the fixing plates are radially connected with the outer peripheries of the connection discs and uniformly distributed along the outer peripheries of the connection discs; the fixing plates and the guide rods are provided with long-mouth grooves respectively, the fixing plates are matched with the long-mouth grooves of the guide rods and fixed through bolts, and the ends of the guide rods are provided with steel wire brushes; and the base is provided with a washing liquor tank, the ends of the guide rods are provided with spray nozzles, and the washing liquor tank is connected with the spray nozzle through a water pipe. By means of the cleaning equipment, the radius of the cleaning device can be adjusted according to pipes of different pipe diameters, and the cleaning device is provided with the different cleaning brushes in combination with washing liquor so that a better cleaning effect can be achieved.