The invention relates to the field of a compound preparation device, and in particular relates to a reaction device used for synthesis of tert butyl amine. The device includes a tubular reactor R-101, a nitrogen steel cylinder, a storage tank V-1 , a storage tank V-2, a condensate tank V-3, a buffer tank V-4, a gas-liquid separation tower T-201, a condenser HE-1, a vaporizer V-01 and a vaporizer V-02; the device is used for real-time monitoring of dynamic changes of reaction parameters, and data is accurate and reliable; and according to the detection data, the pump flow rate is timely adjusted to ensure the stability of material ratio before a reactor. Advantages are as follows: 2, by optimization of a gas pipeline system and integration of a pressurized pipeline and a purge pipeline, the frequency of gas pipe removal is reduced, the process is simplified, the risk of leakage is reduced, and the safety factor of the operating process is improved; and 3, a mixed material is used for feeding, and can be directly recycled, compared with respective recovery of ammonia and isobutene, energy consumption is reduced, the number of towers is reduced, and the cost of investment is reduced.